CURRENT RESEARCH STUDIES

An Open-Label, Multicenter, Outpatient Extension Study to Evaluate the Safety and Tolerability of Staccato Alprazolam in Study Participants 12 Years of Age and Older with Stereotypical Prolonged Seizures (EP0165) 

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of IV Ganaxolone in RSE Patients Who Have Failed Benzodiazepines and Two or More Second Line Intravenous Antiepileptic Drugs (AEDs)

Study seeks to test the effectiveness and usability of a novel gait tracking system, called Sensoria Walk, for individuals that use lower limb prosthetics for mobility. The system consists of pressure-based textile sensors integrated into standard socks and an inertial measurement unit (IMU) that attaches to the prosthetic and measures limb movement. Study procedures include collection of walking metrics, completion of questionnaires and collection of demographic information.

FitMi AD: a safe and motivating computer-guided exercise system for individuals with MCI or mild dementia due to Alzheimer's disease

A Prospective, Multicenter, Single Blind, Two-Arm Randomized Sham-Controlled Clinical Study to Provide Comparative Evidence Assessing Clinically Meaningful Benefit in the Treatment of Subjects with Neurogenic Lower Urinary Tract Dysfunction (NLUTD) with the SCONE Device

Study of patients undergoing brain or spinal surgery to collect hemodynamic data using functional ultrasound (fUS) while in the resting state and when receiving either peripheral stimulation or spinal stimulation. Additionally, they would like to to determine if fUS can detect changes in spinal cord activity during bladder filling and voiding. Study activities will differ depending on the surgery being done on the subject. Patient undergoing surgery for insertion of a spinal cord stimulator will have spinal cord stimulation (SCS), transcutaneous spinal cord stimulation (TCS) and peripheral nerve stimulation (PNS). For surgeries that do not involve insertion of a spinal cord stimulator, only PNS and TCS will be done.

Study would like to learn the relationship between empowerment and nurse-driven protocols called Standardized Procedure Standardized Guidelines (SPSG)using a combination of qualitative and quantitative approaches. A validated survey will first be distributed among nursing staff working in the Ambulatory services then a face-to-face interview will be conducted in a subset of subjects.

Study would like to understand the meaning of 'Goal Attainment' from the lived experiences of patients by conducting a one-time interview among those recently discharged (within one year) or currently admitted at RLA.

This is a study that looks into the cognitive function of patients pre- and post-cranioplasty using imaging and Cognivue, which is a set of computer-based questionnaires that assesses cognitive function.

This is a multi-part study designed to enhance pain management strategies in patients with spinal cord injury. Phase 1 involves development of strategies and will include discussions, explorations, beta-testing and feedback from interventions addressing pain issues of SCI patients. Phase 2 involves randomization to an immediate intervention group and a delayed entry control group.

Multi-center study that would like to (1) validate a questionnaire-based clinical decision-making tool for bowel dysfunction in the acute/subacute population with traumatic SCI and (2) use the tool from discharge through their first year post-injury to describe the progression of bowel dysfunction and if the tool can prompt changes in bowel management when indicated.

This study would like to quantify the effect of bowel dysfunction on bowel-related quality of life (QOL) in individuals with SCI and determine the relationships between bowel-related QOL and modifiable and non-modifiable patient attributes. In addition, they would like to determine the natural history of Neurogenic Bowel Dysfunction Score (NBDS) and bowel-related QOL in the early (0-3 years) period after SC and assess the relationship between neurogenic bladder dysfunction (NBD) and bowel-related QOL.

This is a pilot project that will utilize transcutaneous spinal cord stimulation (TSCS) technology in conjunction with various rehabilitation activities and biomechanical assessments to evaluate TSCS' ability to improve lower extremity function in individuals with SCI versus standard clinical practice.

This retrospective chart review would like to create a registry that will organize detailed information (demographic and clinical parameters) about patients at Rancho who sustained a spinal cord injury. De-identified data will be sent to the National Spinal Cord Injury Statistical Center in Birmingham, Alabama.

This study seeks to enable informed decisions on mobility training by arming clinicans with an understanding of functonal mobility changes over the first year post spinal cord injury and their relationship to patient characteristics and impact on participation. Study will determine the predictve ability of objective measures of non-purposeful activity, ambulatory ability, wheelchair skills and track changes in mobility in the year following injury.